Locations are London, Scotland, Turkey and China. The Bond Girl names are Severin and Eve, played by Bérénice Marlohe and Naomie Harris. No word on the name of the villain, who will be played by Javier Bardem. The official plot description reads:
"In SKYFALL, Bond's loyalty to M is tested as her past comes back to haunt her. As MI6 comes under attack, 007 must track down and destroy the threat, no matter how personal the cost."
You can read the full press release here.