Speaking to BBC Radio 5 live, Horowitz said the opening line was the "only reason" he wanted to write the novel, which is expected to be released in 2018 - but he could not reveal the book's first words. He said one of the first chapters of the book will be based on a story outline written by Ian Fleming for a TV series that was never made.
This man knows how to tease!
You can listen to the full interview at BBC Radio 5. Horowitz's "James Bond book 2" will be released by Jonathan Cape in the UK in 2018.
UPDATE: I think we now know what that first line is. Anthony's correct. It's a killer!